If you do not understand racism (white supremacy) and how it works, everything else you understand will only confuse you. - Neely Fuller

We need something to clarify everything for us, because we get confused...but if we use the concept of Asili, we will understand that whatever it is they are doing, whatever terms they use, however they come at you, you need to be thinking about what? How is this going to facilitate their power and help them to dominate me? -Marimba Ani

Sunday, January 23, 2022

Remdesivir (Veklury), Somewhat Simplified & Clarified
What Is It & How Is It Made?
Unity Consciousness #2625

(9azzzzv of 11)

Remdesivir is an antiviral drug administered intravenously. It is formulated by humans who did so by combining portions of plant molecules.

How Remdesivir Is Made

Per Development of Remdesivir (Brand name: Veklury)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202249/
Excerpts subject to slight paraphrasing. My comments are specifically noted and/or are included in brackets [ ] when distinction is important.

”Remdesivir was developed by Gilead Sciences, Inc. and emerged from a collaboration between Gilead, the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). [Thus, of course Remdesivir is going to be approved as a top treatment drug for COVID because the USA government has to justify spending years and billions of taxpayer dollars developing this drug and then allowing Gilead to profit].

According to braggadocios take-all-the-credit Gilead, at https://www.gilead.com/news-and-press/press-room/press-releases/2022/1/fda-approves-veklury-remdesivir-for-the-treatment-of-nonhospitalized-patients-at-high-risk-for-covid19-disease-progression , “Veklury (remdesivir) is a nucleotide analog invented by Gilead, building on more than a decade of the company’s antiviral research.”

Gilead and the two USA government agencies mentioned above, sought to identify therapeutic agents for treating RNA-based viruses that maintained global pandemic potential, such as those that indeed emerged following the initiation of the program, including Ebola and the Coronaviridae family viruses exemplified by Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS).” [thus virus pandemics didn't start to arise on a regular frequent basis until humans began another project of manipulating plant molecules in the event a pandemic occurred, then several viral outbreaks occurred leading up to COVID-19]

“As a starting point for discovery, a library of approximately1,000 small molecules focused around nucleoside analogues was compiled, based on prior knowledge of effective antiviral compounds targeting RNA viruses.
Nucleosides are poorly cell-permeable [when toyed with] (and therefore can have a low hit rate in cell-based screens such as antiviral screens), so modified nucleosides such as monophosphate, ester, and phosphoramidate prodrugs composed a significant portion of the library. Such prodrugs are typically more permeable and metabolized to liberate the nucleoside or phosphorylated nucleoside within cells.”

“While the data from the original full screen does not appear to have been disclosed, a modified adenosine C-nucleoside hit, along with a prodrug form of the monophosphate of adenosine C-nucleoside, was found to be highly potent and, this combination was later renamed “Remdesivir.”
Remdesivir was found effective against: yellow fever virus (YFV), Dengue virus type 2 (DENV-2), influenza A, parainfluenza 3, and SARS.”

“With the demonstration that Remdesivir possessed broad activity against RNA viruses, multiple groups assessed the drug's antiviral activity against coronaviruses. Antiviral activity was confirmed against SARS, MERS zoonotic coronaviruses, as well as the circulating human coronaviruses of the common cold. Furthermore, it was demonstrated that Remdesivir had both prophylactic [preventative] and therapeutic [curative] activity against MERS in a nonhuman primate.”

Remdesivir's effects on humans have been summarized by the European Medicines Agency. Remdesivir is administered intravenously with an initial dose followed by a daily maintenance dose for up to 10 days.”

“Nonhuman animal models supported the effectiveness of Remdesivir against SARS-CoV-2 and related coronaviruses. An additional study demonstrated in vivo efficacy of Remdesivir at inhibiting viral replication and reducing viral related pathology against related coronaviruses [variants, siblings and cousins]. These findings, along with the safety profile of Remdesivir in the clinical trial assessment against Ebola, support the evaluation of Remdesivir as a potential therapeutic drug for repurposing against the SARS-CoV-2 pandemic.” [This last sentence in regards to Ebola contradicts the next paragraph]

Driven by the Ebola (EBOV) outbreak in 2014 and based on in vitro and animal model in vivo efficacy against EBOV, Gilead Sciences initiated clinical evaluation of Remdesivir for EBOV. Gilead pursued FDA evaluation under the FDA’s Animal Rule, permitting the reliance on efficacy findings from animal studies for drugs in which it is not feasible or ethical to conduct human trials. As such, Remdesivir was included in a randomized, controlled trial of Ebola virus therapeutics in patients within the Democratic Republic of the Congo. [because Africans are animals, not humans. This is an example of the ongoing psychopathic sociopathic mindset, that to them, seems normal].
However, midstudy primary analyses found Remdesivir inferior to the antibody based treatments, with respect to mortality, and the Remdesivir intervention arm was terminated.”

Conclusion

So out of all the natural products found in plants and the plants themselves, not a single one has been approved as a treatment for SARS-CoV-2 or as a treatment for any virus. Yet thousands of those same plants are used in the making of prescription and over-the-counter drugs humans can patent and sell and maintain the illusion that they know more than God, their parents, Mother and Father Nature and traditional healers, the NGAs.

You might get lucky and have a medical person tell you to drink cranberry juice to fight off a urinary tract infection (UTI).

You might get lucky and have someone tell you to drink ginger ale for an upset stomach but they won't tell you to boil some ginger and drink ginger tea.

When was the last time a doctor told you to eat more fruits and vegetables, drink water, get sunlight, reduce toxins, and so on?

Isn't it a strange human world where they will pay for prescription drugs but health insurance will not pay for you to purchase fruits and vegetables as medicine or pay for you to have a fruit tree or other perennial food planted in your yard, both of which are cheaper and healthier.

And you still think these people want to help you by offering you free COVID-19 vaccines.